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12 Aug Emmanuel Ledesma: Chemistry, Week Seven

Posted at 23:31h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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I cannot believe this was my last week in the lab and I am sad to see it all come to an end. This week we primarily focused on making our posters to present on our last day. We were to make three posters per...

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05 Aug Emmanuel Ledesma: Chemistry, Week Six

Posted at 17:23h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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This week in the lab we completed our task of ranking the 12 ligands in order from the lowest IC50 to the highest. We were able to accomplish this by using three analysis methods we chose. The methods included: free energy, secondary structure, and hydrogen...

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29 Jul Emmanuel Ledesma: Chemistry, Week Five

Posted at 18:00h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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This week in lab, the fun had began as we started to do research for the lab. The first half of my internship, I had been learning the fundamentals and different analysis methods used to analyze proteins. Our task now was to find new methods...

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22 Jul Emmanuel Ledesma: Chemistry, Week Four

Posted at 18:17h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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This week in the lab we continued working with two more analyses to run on our Hsp90 systems. These will be the last analyses that our mentors will teach us. The main purpose of all of these analyses we have learned are to see if...

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15 Jul Emmanuel Ledesma: Chemistry, Week Three

Posted at 17:59h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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My third week in the lab consisted of working with three new analysis. The first is called System Energy Analysis. System Energy Analysis focuses on analyzing the correlation of system energy with measured IC50 values. What this basically does is it takes the average energy...

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08 Jul Emmanuel Ledesma: Chemistry, Week Two

Posted at 18:25h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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The second week of my internship was just as exciting as my first. This week we primarily focused on analyses that we have to run in Molecular Dynamics (MD) simulations. Molecular Dynamics simulations are used to see how structures change over time compared to the...

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01 Jul Emmanuel Ledesma: Chemistry, Week One

Posted at 21:23h in 2018 Interns, Emmanuel Ledesma, Pinhead Intern Blogs by jessica 0 Comments
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My name is Emmanuel Ledesma and I am one of the interns from Olathe High School. Myself and Tyler, another Pinhead Intern, are working with the Amaro Lab at the University of California, San Diego(UCSD). My journey started on Sunday, June 24, as I flew...

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