Hey again, if you missed my previous blogs, I’m Evan Strand, and I’m interning at the Doris Neuroscience Center with Scripps in San Diego. The lab that I’m working with is focused changes in metabolism effect the brain.
It was nice that my dad was able to visit me for Fourth of July, and he made me realize that I haven’t explained much of basics of the experiment I’m helping with. As I’ve said before, the experiment I’m working on is testing how different chemicals and proteins affect how much the mouse eat and how much of that food is turned into body weight. There are a total of 111 (112 if you count the mouse that died) mice that we split into four rows, each row containing seven cages, and each cage containing four mice. To keep things simple I’ll call the rows, Row 1, Row 2, Row 3, and Row 4. Rows 1 and 2 have their injections in the hippocampus while Rows 3 and 4 are injected into the cerebral cortex to see if where the mice are injected make a difference. Then, Rows 1 and 3 are fed the normal chow (Image B) while Rows 2 and 4 are given the high fat diet (Image A). I also realized that group where the one mice died was actually not a group we were testing, but was in fact, our positive control.
Image A
Image B
Also, this week our lab celebrated one of our scientist’s first scientific paper, we all got matching sweaters with our labs logo, and the head of our lab, Dr. Ye Le, left to go attend a science convention in Europe, so I won’t see him for my last week at my internship.
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